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Dcis

Overview

A woman's breasts are made up of 15 to 20 sections of tissue, like the petals of a flower. These sections, called lobes, have smaller parts called lobules. The lobules create the milk for breastfeeding. Tiny tubes, called ducts, carry the milk to a storage area just under the nipple.

DCIS, or ductal carcinoma in situ, is a very early stage of breast cancer. In DCIS, cancer cells are trapped inside a milk duct. They haven't spread to the surrounding breast tissue. Sometimes you'll hear it called non-invasive, pre-invasive, or stage 0 breast cancer.

Doctors often find DCIS during a mammogram, a special X-ray test used to check for breast cancer. A mammogram might also be used to look at a breast lump. While DCIS has a low chance of spreading and becoming a serious problem, it still needs to be evaluated and treated.

Treatment for DCIS usually involves surgery. Sometimes, surgery is combined with radiation therapy or hormone therapy. These treatments help reduce the risk of the cancer coming back or spreading. The specific treatment plan depends on many factors, including the size and location of the DCIS, and the individual's overall health.

Symptoms

DCIS, or ductal carcinoma in situ, is a type of early breast cancer that often has no noticeable symptoms. This means you might not feel anything unusual. However, in some cases, you might experience a breast lump or a discharge from your nipple that's bloody.

Often, DCIS is discovered during a mammogram. A mammogram is an X-ray of your breasts. Doctors look for tiny calcium deposits, sometimes called calcifications, which can show up as tiny white flecks on the X-ray. These calcifications are often a sign of DCIS.

If you notice any changes in your breasts, it's important to see a doctor or other healthcare provider right away. Possible changes to watch out for include:

  • A lump or a thickening in the breast tissue: This might feel like a small, hard area.
  • Changes in the skin of the breast: This could include puckering or dimpling, making the skin look uneven or abnormal.
  • Thickening of the breast tissue: This might feel like a denser area under the skin.
  • Nipple discharge: Any discharge from your nipple, especially if it's bloody, should be checked by a doctor.

It's a good idea to talk to your healthcare provider about when you should start getting mammograms and how often you should have them. Most doctors recommend starting routine breast cancer screenings around age 40. However, your individual risk factors and family history might influence when and how often you should be screened. Be sure to discuss this with your doctor.

When to see a doctor

If you notice any changes in your breasts, like a lump, unusual skin texture (like puckering), a thickening under the skin, or nipple discharge, see your doctor or other healthcare provider right away.

Talk to your doctor about when you should start getting screened for breast cancer and how often. Most doctors recommend starting routine breast cancer screenings in your 40s. This is important because early detection can greatly improve treatment outcomes.

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Causes

DCIS, or ductal carcinoma in situ, is a type of early breast cancer. We don't fully understand what causes it.

Imagine your body's cells like tiny workers. Their DNA is like a set of instructions telling them how to grow, multiply, and when to stop. In healthy cells, the DNA instructions are clear and consistent. They multiply at a specific rate and die when they're supposed to. However, in DCIS, something goes wrong with the DNA instructions within the cells lining the milk ducts in the breast. These changed instructions tell the cells to grow and divide much faster than normal, and they don't die when they should. This rapid growth leads to a buildup of abnormal cells inside the milk duct.

Crucially, in DCIS, these abnormal cells haven't yet broken through the walls of the milk duct and spread to other breast tissue. They're still confined to the duct.

Doctors don't know precisely what triggers these DNA changes. Several factors might play a role. This could include things like lifestyle choices, exposure to environmental factors, and whether certain genetic changes are passed down through families. More research is needed to fully understand the causes.

Risk factors

Certain things can make it more likely you'll develop ductal carcinoma in situ (DCIS), a type of early breast cancer. Here are some factors that might increase your risk:

Family History: If close relatives (parents, siblings, children) have had breast cancer, especially at a young age or if multiple family members have been diagnosed, your risk goes up. However, most people with breast cancer don't have a family history.

Personal History: Having had breast cancer in one breast raises your chances of getting it in the other.

Previous Breast Conditions: Some breast conditions, like lobular carcinoma in situ (LCIS) or atypical hyperplasia, are linked to a higher risk of breast cancer. If a biopsy shows one of these, your doctor will discuss your increased risk.

Age of Onset: Starting your period before age 12 or reaching menopause after age 55 may slightly increase your risk.

Gender: Women are much more likely to develop breast cancer than men. Everyone has some breast tissue, meaning anyone can get breast cancer.

Breast Density: Breasts are made of fatty and dense tissue. Dense tissue includes milk glands, ducts, and fibrous material. If your breasts have more dense tissue than fatty tissue, mammograms might not easily spot cancer. If your mammogram shows dense breasts, your doctor may suggest additional tests to check for cancer.

Alcohol Consumption: Drinking alcohol can increase your risk of breast cancer.

Motherhood: Having children later in life (after age 30) or never having children might increase your breast cancer risk compared to those who have had one or more pregnancies.

Age: Your risk of breast cancer generally goes up as you get older.

Inherited Gene Changes: Some gene changes, like BRCA1 and BRCA2, can be passed down and significantly increase the risk of breast and other cancers. But not everyone with these changes will develop cancer.

Hormone Therapy: Taking hormone replacement therapy (HRT) to manage menopause symptoms, especially those containing both estrogen and progesterone, may slightly raise your breast cancer risk. This risk goes down when you stop the therapy.

Weight: Being obese is associated with a greater likelihood of breast cancer.

Past Radiation: Radiation therapy to the chest during childhood or young adulthood can increase your breast cancer risk.

It's important to talk to your doctor about your individual risk factors and how to best manage your breast health. They can discuss specific tests or monitoring strategies that might be helpful for you.

Prevention

Making lifestyle changes might reduce your chances of developing ductal carcinoma in situ (DCIS), an early form of breast cancer. Here are some things you can consider:

Breast Cancer Screening: Talk to your doctor about when you should start getting screened for breast cancer. Discuss the potential benefits and downsides of different screening tests. Working together, you can choose the best screening plan for you.

Breast Awareness: Getting to know your breasts can help. Regularly checking your breasts for any changes, such as lumps or unusual sensations, is called a breast self-exam. This helps you become familiar with how your breasts normally feel. If you notice anything new or unusual, tell your doctor immediately. Breast self-exams can't prevent breast cancer, but they can help you spot any changes more easily.

Alcohol: If you drink alcohol, limit it to one drink or less per day. There's no known safe amount of alcohol for preventing breast cancer, so if you're very worried about your risk, you might choose not to drink at all.

Exercise: Aim for at least 30 minutes of moderate-intensity exercise most days of the week. If you haven't been active for a while, talk to your doctor before starting a new exercise routine. Start slowly and gradually increase the intensity and duration of your workouts.

Hormone Therapy: Combination hormone therapy might slightly increase your risk of breast cancer. Talk to your doctor about the potential benefits and risks of using hormone therapy. If you're experiencing menopausal symptoms, you might decide the benefits outweigh the risks. If you do use hormone therapy, use the lowest dose possible for the shortest time needed.

Weight Management: Maintaining a healthy weight can help lower your breast cancer risk. If you need to lose weight, talk to your doctor about healthy ways to do so. This usually involves eating fewer calories and gradually increasing physical activity. Consult with a healthcare professional for personalized advice.

Diagnosis

Understanding Breast Calcifications and Biopsies

Small calcium deposits in the breast, called calcifications, appear as white spots on a mammogram (an X-ray of the breast). Most calcifications are harmless (benign). They might be large, round, and well-defined. However, tiny, irregular clusters of calcifications might be a sign of cancer.

If a mammogram shows something unusual, further tests are needed. This often starts with a diagnostic mammogram. This detailed X-ray exam of the breasts looks at the area of concern from multiple angles and at higher magnification. This helps to get a clearer picture of any calcifications.

Sometimes, a breast ultrasound is also done. Ultrasound uses sound waves to create images of the inside of the body. This helps healthcare providers understand the area of concern better.

If more investigation is needed, a biopsy is the next step. A biopsy removes a small sample of breast tissue for lab analysis. There are different types of biopsies.

  • Stereotactic Breast Biopsy: This biopsy uses X-rays (mammograms) to pinpoint the exact location of the suspicious area. The breast is pressed between plates, and the X-rays help pinpoint the exact spot for the needle. A tiny needle is then used to remove a tissue sample.

  • Core Needle Biopsy: A hollow needle is inserted into the breast to collect a sample of tissue. This is often used for suspicious lumps. The sample is sent to a lab where a pathologist (a doctor specializing in examining tissues) looks for cancer cells and assesses how aggressive they might be. An imaging test, like ultrasound, often guides the needle to the right spot.

  • Ultrasound-Guided Breast Biopsy: This biopsy is similar to a core needle biopsy but uses ultrasound images to guide the needle to the precise location.

The lab results from a biopsy tell healthcare providers if there are cancer cells present and, if so, how serious they are. If cancer cells are found, the results help determine the best treatment plan.

Important Note: Finding unusual calcifications or lumps on a mammogram doesn't automatically mean you have cancer. Many calcifications are harmless. Further tests, like biopsies, are needed to determine the nature of the finding. Your healthcare provider will discuss the results and recommend the next steps, if necessary.

Treatment

Treating Ductal Carcinoma In Situ (DCIS)

Ductal carcinoma in situ (DCIS) is a non-invasive form of breast cancer, meaning the cancer cells haven't spread beyond the milk ducts. While it's not considered a major threat in its early stages, it still needs treatment to prevent it from progressing to a more aggressive form of cancer. Treatment options focus on removing the abnormal cells or reducing their growth.

Surgery Options:

  • Lumpectomy (Breast-Conserving Surgery): This surgery removes the cancerous area and some surrounding healthy tissue. The goal is to keep as much of the breast as possible. Most lumpectomy patients also receive radiation therapy as a follow-up, increasing the chances of successful treatment. While the risk of the cancer returning after lumpectomy is slightly higher compared to a mastectomy, the chances of survival are similar with both methods. Other treatment options like hormone therapy may be considered depending on individual circumstances.

  • Mastectomy: This involves removing the entire breast. A mastectomy may be recommended if the DCIS is extensive, in multiple areas, or if the cancer cells are close to the edges of the tissue sample. It may also be preferred by some patients, especially if radiation therapy is not an option. A mastectomy may also be necessary if there's a concern that the cancer has spread beyond the milk ducts.

Radiation Therapy:

High-powered energy beams, such as X-rays or protons, are precisely targeted at the affected area to kill any remaining cancer cells. External beam radiation is the common method. It's often used after a lumpectomy to reduce the risk of recurrence. However, if the DCIS is small, slow-growing, and completely removed during surgery, radiation might not be necessary.

Hormone Therapy:

Some breast cancers, including some DCIS, are sensitive to hormones like estrogen and progesterone. Hormone therapy uses medication to block these hormones, reducing the cancer cells' ability to grow and potentially reducing the risk of recurrence or the development of new breast cancers. This is typically used after surgery or radiation. Important discussions with your healthcare team about the specific types of hormone therapy and their risks and benefits are crucial.

Important Considerations:

  • Lymph Node Removal: DCIS is typically non-invasive, so lymph node removal under the arm is usually not required. Lymph nodes may be removed if there's a suspicion of the cancer spreading beyond the breast ducts or if a mastectomy is performed.

  • Treatment Choices: The decision between lumpectomy and mastectomy often depends on the size and location of the DCIS, the patient's health, and personal preferences.

  • Complementary and Alternative Medicine (CAM): While no CAM treatments have been proven to cure DCIS, some therapies, like art therapy, exercise, meditation, and others, may help with managing the emotional and physical side effects of treatment. It's essential to discuss these options with your healthcare team to ensure they don't interfere with your primary treatment plan.

  • Coping with Diagnosis: A DCIS diagnosis can be overwhelming. It's crucial to ask questions, research your options, and talk to trusted loved ones, healthcare professionals, or support groups to navigate this process. You're not alone. Communicating your needs and concerns with your healthcare team is essential for making informed decisions.

This information is for general knowledge and understanding only, and does not constitute medical advice. Always consult with your doctor or other qualified healthcare professional for personalized advice and treatment options.

Self-care

A DCIS (ductal carcinoma in situ) diagnosis can be upsetting. It's important to feel in control of your care. One way to do this is to learn about DCIS. Understanding what it is and how it affects you can help you make informed decisions about treatment. This means asking your doctor and other healthcare providers many questions about your specific situation, including the pathology report. Use this information to research your treatment options. This knowledge can help you feel more confident in making choices about your care.

However, some people don't want to know all the details. If this is how you feel, tell your healthcare team. It's perfectly okay to not want to know all the medical details.

It's also important to talk about how you feel. Find someone you trust who can listen, like a friend, family member, clergy member, or counselor. If you need help finding someone to talk to, ask your doctor for a referral to a counselor or therapist who specializes in cancer support.

Having a strong support system is crucial. Your friends and family can be a great source of comfort and assistance during treatment. As you share your diagnosis, you'll likely receive offers of help. Think about what kind of help you might need or want, such as someone to listen to you, help with meals, or errands. Let those around you know what you need.

Preparing for your appointment

If you have any breast-related symptoms that concern you, see a doctor right away. If tests suggest you might have ductal carcinoma in situ (DCIS), a type of non-invasive breast cancer, your doctor will likely refer you to a specialist. These specialists can include:

  • Breast health specialists: Doctors who focus on breast health.
  • Breast surgeons: Doctors who perform surgery on the breasts.
  • Radiologists: Doctors who specialize in imaging tests like mammograms.
  • Oncologists: Doctors who specialize in cancer treatment.
  • Radiation oncologists: Doctors who use radiation to treat cancer.
  • Genetic counselors: Experts in inherited conditions, including cancer risks.
  • Plastic surgeons: Doctors who perform reconstructive surgery, sometimes needed after breast cancer treatment.

Getting Ready for Your Appointment:

It's helpful to prepare for your appointment with information about your health history. This will help your doctor understand your situation better.

  • Medical History: Write down a list of all past breast conditions, even benign ones (not cancerous). Also, note any radiation therapy you've had, no matter when.
  • Family History: List any family members who've had cancer. Include their relationship to you, the type of cancer, their age when diagnosed, and if they survived. This helps assess your risk.
  • Medications: Make a list of all medications, vitamins, and supplements you're taking.
  • Hormone Replacement Therapy (HRT): If you've used or are currently using HRT, tell your doctor.
  • Bring a Support Person: Bringing a friend or family member can be helpful. They might remember details you miss or forget during the appointment.
  • Prepare Questions: Write down questions to ask your doctor. This ensures you get all the information you need. Prioritize the most important questions in case time runs out.

Important Questions to Ask Your Doctor:

  • Diagnosis: Do I have breast cancer? What type and stage is it?
  • Treatment: What treatment do you recommend? What are the possible side effects? How effective is the treatment?
  • Specific Treatments: Am I a candidate for tamoxifen? Am I at risk of the DCIS returning or becoming invasive breast cancer? How will you treat DCIS if it returns?
  • Follow-up: How often will I need follow-up appointments?
  • Lifestyle: What lifestyle changes might help reduce my risk of recurrence?
  • Second Opinion: Do I need a second opinion? Should I see a genetic counselor?

What Your Doctor Will Ask You:

Be prepared to answer questions about your symptoms and health history, such as:

  • Menopause: Have you gone through menopause? Are you using or have you used hormone treatments for menopause?
  • Past Breast Procedures: Have you had other breast biopsies or surgeries?
  • Other Medical Conditions: Have you been diagnosed with any other medical conditions?
  • Family History: Do you have a family history of breast cancer? Have you or your female relatives been tested for BRCA gene mutations?
  • Radiation Exposure: Have you ever had radiation therapy?
  • Lifestyle: What's your typical diet, including alcohol intake? How active are you?

By being prepared and asking the right questions, you can work with your doctor to understand and manage your DCIS.

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Disclaimer: August is a health information platform and its responses don't constitute medical advise. Always consult with a licenced medical professional near you before making any changes.

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