Health Library Logo

Health Library

Head And Neck Cancers

Overview

Head and neck cancers are a group of different types of cancer that develop in the head and neck region. These cancers begin when cells grow abnormally, spreading and damaging healthy tissues. Common areas affected include the mouth, throat, sinuses, and salivary glands. However, other areas in the head and neck can also be affected, and these cancers may sometimes be grouped together as head and neck cancers.

Importantly, "head and neck cancer" isn't a single disease, but rather a broad category of cancers sharing similar characteristics. This means many of these cancers have overlapping risk factors and treatment approaches. The most common type of head and neck cancer arises from squamous cells. These flat, thin cells form the outer layer of skin and also line the inside of the nose, mouth, and throat. Cancers originating from squamous cells are called squamous cell carcinomas. Less commonly, head and neck cancers can start in other types of cells.

The best treatment for head and neck cancer varies greatly. Several factors are considered, including: where the cancer is located, its size, and the specific type of cell involved. Your overall health is also taken into account. Treatment options can include surgery, radiation therapy, chemotherapy, targeted therapy, and sometimes a combination of these. The specific treatment plan is tailored to each individual patient.

Symptoms

Head and neck cancers can start in various parts of the head and neck, such as the mouth, throat, sinuses, or salivary glands. The specific symptoms depend on exactly where the cancer develops.

Common symptoms in the mouth and throat area include:

  • A lump in the neck: This lump is often painless and can be felt under the skin.
  • A mouth sore that won't heal: This could be a persistent, unusual sore in your mouth.
  • Coughing up blood: Blood in your cough is a serious sign and needs medical attention.
  • Hoarse voice: If your voice sounds unusually scratchy or rough, this could be a symptom.
  • Loose teeth: While not always a cancer symptom, loose teeth that don't have a clear cause could be a sign.
  • Pain when swallowing: Difficulty or pain when eating or drinking can be a warning sign.

Symptoms related to the nose area might include:

  • Nosebleeds: Frequent or unusual nosebleeds could be a sign of something more serious.
  • Stuffy or blocked nose that doesn't clear up: A persistent blocked nose is worth checking out.

Other potential symptoms to watch out for include:

  • A sore on the face, neck, or lips that doesn't heal: Any skin sore that lingers needs to be examined.
  • Ear pain: Persistent ear pain, especially if it's not due to an obvious cause, could be a symptom.
  • Unexplained weight loss: Losing weight without trying to could be a sign of an underlying health problem, including cancer.

Important: If you experience any of these symptoms, it's crucial to make an appointment with a doctor or other healthcare professional as soon as possible. Early detection is key to successful treatment. Don't hesitate to seek medical advice if you're concerned about your health.

When to see a doctor

If you're feeling unwell and something is bothering you, it's important to schedule a visit with a doctor or other medical professional. Don't hesitate to get checked out. This is a good way to get the best possible care and address any concerns you might have.

Causes

Head and neck cancers are a group of cancers that affect areas like the mouth, throat, sinuses, and salivary glands. Scientists aren't completely sure what causes them, and the exact cause might vary depending on where the cancer starts.

Basically, head and neck cancers begin when a cell in the head or neck area has its DNA changed. DNA is like a set of instructions for the cell, telling it how to grow, multiply, and when to die. Healthy cells follow these instructions carefully, growing and dividing at a normal rate and dying at the right time. But in cancer cells, the DNA changes, giving the cell new, incorrect instructions. These new instructions tell the cancer cell to make more and more cells very quickly, and they also tell the cell to ignore the signals that tell healthy cells to die. This uncontrolled growth leads to too many cells building up.

These extra cells can form a lump called a tumor. This tumor can grow, pushing into and damaging nearby healthy tissues. Over time, some cancer cells can break off from the main tumor and travel to other parts of the body. When this happens, the cancer is said to have spread, and it's called metastatic cancer.

Risk factors

Certain factors increase the chance of getting head and neck cancers. These cancers can develop in various parts of the head and neck, including the mouth, throat, sinuses, and salivary glands. Several risk factors are common across these different types.

Some key risk factors include:

  • Tobacco use: Smoking cigarettes, cigars, pipes, or using chewing tobacco or snuff significantly increases the risk of head and neck cancers. All forms of tobacco contain harmful chemicals linked to cancer.

  • Heavy alcohol use: Drinking a lot of alcohol frequently raises the risk of many head and neck cancers. The more you drink and the more often you drink, the higher the risk.

  • Human Papillomavirus (HPV): HPV is a common virus often spread through sexual contact. For many, HPV causes no health problems and disappears on its own. However, in some, it can lead to cell changes that increase the risk of several types of cancer, including cancers of the throat.

  • Exposure to air pollutants: Breathing in certain chemicals in the air, whether at home or work, can increase the risk of cancer in the nose and sinuses. These chemicals can be found in various products and industrial settings.

  • Sun and tanning bed exposure: Ultraviolet (UV) light from the sun, and tanning beds, increases the risk of skin cancers in the head and neck region. Prolonged exposure to this type of light can damage skin cells, potentially leading to cancer.

Understanding these risk factors can help individuals take steps to lower their risk of developing head and neck cancers.

Prevention

Preventing Head and Neck Cancers: Simple Steps You Can Take

Head and neck cancers can start in different places, such as your mouth, throat, sinuses, and salivary glands. These cancers are serious, so taking steps to lower your risk is important.

One of the best ways to reduce your risk is to avoid tobacco use. If you don't smoke or use other tobacco products, don't start. If you do use tobacco, make a plan to quit. Talk to your doctor or a healthcare professional about resources and strategies to help you quit. This could include counseling, medication, or support groups.

Alcohol can also increase your risk. If you choose to drink, do it in moderation. For healthy adults, this means a maximum of one drink per day for women and two drinks per day for men. A "drink" is generally equivalent to a 12-ounce beer, a 5-ounce glass of wine, or a 1.5-ounce shot of liquor.

Certain viruses, like HPV (human papillomavirus), can also cause head and neck cancers. Getting vaccinated against HPV can help lower your risk. Talk to your doctor about whether the HPV vaccine is appropriate for you. This is especially important for people who are not yet sexually active.

Finally, protecting your skin from the sun is crucial. Wear a hat with a wide brim to shield your head and neck. Use a sunscreen with a sun protection factor (SPF) of 30 or higher, even on cloudy days. Apply a generous amount of sunscreen and reapply every two hours, or more often if you're sweating or swimming. Regular sun protection helps prevent skin damage that can contribute to cancer risk.

Diagnosis

Diagnosing head and neck cancers often starts with a physical examination of the head and neck. Doctors look for any unusual sores, lumps, or swelling in the area. This might involve checking the mouth with a light and mirror, feeling the neck for abnormalities, or even using a small camera to look inside the throat or nose.

To get a better understanding of the cancer's location and size, imaging tests are frequently used. These tests create pictures of the inside of the body, helping doctors see the cancer. Common imaging tests for head and neck cancers include CT scans (computed tomography), MRI scans (magnetic resonance imaging), and PET scans (positron emission tomography). These scans provide detailed images that help pinpoint the cancer's location and extent.

Sometimes, a small sample of tissue needs to be removed and examined under a microscope. This procedure is called a biopsy. The method used to collect the tissue sample depends on the location of the cancer. For accessible cancers, a small piece of tissue might be cut out. In other cases, a needle is used to take a sample of cells from the cancer. Special tools are also available for collecting samples from the throat or nose.

The tissue sample is sent to a laboratory for analysis. The lab tests the cells to determine if they are cancerous. Further tests may look for specific characteristics of the cancer cells, such as whether they are infected with the human papillomavirus (HPV). This information helps healthcare professionals create a personalized treatment plan.

Mayo Clinic offers expert care for head and neck cancers. Our team of specialists can guide you through every step of the diagnostic and treatment process.

Treatment

Treating Head and Neck Cancers: A Comprehensive Guide

Head and neck cancers are cancers that start in the mouth, throat, sinuses, or salivary glands. One of the main treatments is surgery, where doctors remove the cancer. The goal is to remove all the cancer cells, and often, a small amount of healthy tissue around the tumor is also taken out. This is called a margin, and it helps to make sure all the cancer is gone.

If the cancer has grown into nearby areas and can't be fully removed with surgery, other treatments like radiation therapy or chemotherapy might be used first.

Surgery for head and neck cancers can sometimes affect your ability to eat and talk. Your medical team will try to minimize this. Reconstructive surgery can help rebuild any lost tissue or bone. Rehabilitation specialists can also help you regain your ability to eat and speak.

Radiation Therapy:

Radiation therapy uses high-energy beams, like X-rays or protons, to target and destroy cancer cells. You lie on a table while a machine sends the radiation to specific areas on your body. This treatment might be used after surgery to kill any remaining cancer cells, or it might be the first treatment option if surgery isn't possible.

Chemotherapy:

Chemotherapy uses powerful medicines to kill cancer cells. Sometimes, it's used together with radiation therapy to make the radiation more effective. Chemotherapy can also be used to control cancer that has spread to other parts of the body.

Targeted Therapy:

Targeted therapies use medicines that specifically attack certain chemicals in cancer cells. This can cause the cancer cells to die without harming healthy cells. Targeted therapy may be an option if the cancer has spread.

Immunotherapy:

Immunotherapy helps your body's immune system fight the cancer. Your immune system normally fights off germs and other invaders. Immunotherapy helps your immune system recognize and destroy cancer cells that have hidden from it. This treatment might be used if the cancer has spread.

Palliative Care:

Palliative care focuses on making you feel better during a serious illness like cancer. This care can help with pain, and other symptoms. Palliative care teams include doctors, nurses, and other specialists who work to improve your quality of life. You can receive palliative care at the same time as other cancer treatments, like surgery or chemotherapy.

Clinical Trials:

Clinical trials test new cancer treatments. These trials can help you access the latest treatments, but potential side effects may not be fully known. Talk to your doctor to see if you might be eligible for a clinical trial.

Coping with Cancer:

Dealing with a cancer diagnosis can be scary and overwhelming. Here are some helpful ways to cope:

  • Write down your questions: Bring a list of questions to your appointments.
  • Ask for resources: Your healthcare team can provide reliable information and resources.
  • Bring a support person: Having someone with you can help you remember important details.
  • Involve your loved ones: Keep your friends and family involved in your life.
  • Ask for help: Let your loved ones know what you need help with, whether it's household tasks or simply a listening ear.
  • Seek support: Contact the American Cancer Society or ask your healthcare team for support groups or counselors.

Remember, you're not alone, and there are many resources available to help you and your loved ones through this challenging time. Understanding your treatment options and actively seeking support can make a significant difference in your well-being.

Self-care

Facing a serious illness like cancer can be frightening and worrying. It's completely understandable to feel scared about the future. While it takes time to adjust, there are ways to cope.

Understanding Your Cancer:

One helpful strategy is to ask questions about your cancer. Write down everything you want to know before your next doctor's appointment. Ask your doctor and other medical staff for reliable resources to learn more. Bringing a friend or family member to appointments can be beneficial, helping you remember important details. Learning about your cancer and treatment options will help you feel more in control when making decisions about your care.

Connecting with Loved Ones:

A cancer diagnosis can be stressful for your loved ones too. Keeping them involved in your life is important. They'll likely want to know how they can help. Think about specific tasks you might need help with, such as managing household chores if you're hospitalized, or simply having someone to listen when you want to talk. Let them know what you need.

Finding Support:

Talking to someone who understands what you're going through can be incredibly helpful. Ask your doctor or nurse for a referral to a counselor or medical social worker. Support groups can also offer valuable assistance. Organizations like the American Cancer Society can provide information about support groups, both in person and online. Finding a local group through your medical team is also a great option. These resources can offer comfort, advice, and a sense of community.

Preparing for your appointment

If you have any health concerns, especially those related to your head, neck, or mouth, it's important to see a doctor. If you might have head and neck cancer, you'll likely be referred to specialists.

Who are these specialists?

  • Oral and Maxillofacial Surgeon: This doctor focuses on the face, mouth, teeth, jaws, salivary glands, and neck.
  • ENT (Ear, Nose, and Throat) Specialist or Otolaryngologist: This doctor specializes in the ears, nose, and throat.

Getting Ready for Your Appointment

Appointments with specialists can be quick. To make the most of your time, prepare beforehand:

  • Check for any pre-appointment restrictions: Before your appointment, ask your doctor or clinic if there are any special instructions, like dietary restrictions before tests.
  • List your symptoms: Write down all your symptoms, even those that seem unrelated to the reason you're seeing the doctor. Include when they started, how often they occur, and how severe they are.
  • Gather important personal information: Note any major stresses, recent life changes, or other relevant information that might be helpful.
  • List your medications: Make a list of all medications, vitamins, and supplements you're taking, including the dosages.
  • Bring a friend or family member: Having someone with you can help you remember important details discussed during the appointment.
  • Prepare questions: Your appointment time is limited, so come prepared with a list of questions. Prioritize the most important three, then list the rest in order of importance.

Example Questions to Ask:

  • About the Diagnosis: What kind of cancer do I have? What other tests are needed to confirm the diagnosis?
  • About Treatment: What are my treatment options? What are the potential side effects of each treatment? What might happen if I choose not to have treatment? Is there a single best treatment for my type and stage of cancer?
  • About Follow-up and Care: Should I get a second opinion? Can you recommend any specialists? Am I eligible for clinical trials? Are there any brochures or printed materials I can take home? What websites do you recommend? How will I know if I need a follow-up appointment?
  • About Symptoms: When did your symptoms first appear? Have they been continuous or occasional? How severe are they? What seems to make your symptoms better or worse?

What to Expect From Your Doctor:

Your doctor will likely ask you questions about your symptoms and health history. Be ready to answer questions like:

  • When did your symptoms begin?
  • Are your symptoms constant or do they come and go?
  • How severe are your symptoms?
  • What seems to improve your symptoms?
  • What seems to worsen your symptoms?

By being prepared, you can have a more productive and informative appointment with your healthcare team.

Address: 506/507, 1st Main Rd, Murugeshpalya, K R Garden, Bengaluru, Karnataka 560075

Disclaimer: August is a health information platform and its responses don't constitute medical advise. Always consult with a licenced medical professional near you before making any changes.

Made in India, for the world