Neurofibromas are non-cancerous growths that develop from the nerves outside the brain and spinal cord. They appear as soft, bumpy lumps, either on the skin's surface or just beneath it. These growths can start in any nerve in the body, big or small. Typically, they form inside the nerve itself, like a bulge. Think of the nerve as a wire, and the neurofibroma as a knot in the wire's protective covering, the nerve sheath. Sometimes, these knots can form on multiple nerve bundles, creating a larger, more complex growth called a plexiform neurofibroma.
Most neurofibromas don't cause any noticeable problems. However, if a neurofibroma gets large enough or grows in a way that presses on nearby nerves, it might lead to sensations like pain or numbness. This is because the tumor is putting pressure on the nerve fibers that carry signals to and from the brain.
Importantly, neurofibromas are usually harmless. But, in very rare cases, they can transform into a cancerous tumor. If you have concerns about a lump or any unusual sensations, it's crucial to consult a doctor for proper diagnosis and treatment.
Neurofibromas are growths that can develop from nerves. Often, they don't cause any noticeable problems. If symptoms do appear, they're typically mild.
If a neurofibroma forms on or just below the skin's surface, you might notice:
Larger neurofibromas, or ones pressing on or growing around nerves, can cause more noticeable problems, including:
Some people have a condition called neurofibromatosis type 1 (NF1). This is a genetic condition that can cause many neurofibromas to develop. As a person with NF1 gets older, they may have more of these growths. In people with NF1, a neurofibroma that involves many nerves, called a plexiform neurofibroma, can occur. These plexiform neurofibromas can become very large, causing significant pain and, in some cases, they can become cancerous.
Neurofibromas are tumors that develop in the nervous system. Sometimes, doctors can't pinpoint a reason why they form. Other times, they occur in people who have a genetic condition called neurofibromatosis type 1. These growths are most commonly seen in people between the ages of 20 and 30.
Neurofibromas are growths that can develop in the body's nerves. The only known cause of neurofibromas is a genetic condition called neurofibromatosis type 1, or NF1. People with NF1 often develop multiple neurofibromas, along with other health issues. In many cases of NF1, the condition is inherited from a parent. However, most people with neurofibromas do not have NF1. There are other, unknown causes of neurofibromas in people who don't have NF1.
To figure out if you have a neurofibroma, your doctor will first do a physical exam and look at your medical records.
They might also order imaging tests like a CT scan or MRI. These scans can show where the growth (tumor) is located. CT and MRI scans are good at finding even tiny tumors and showing which parts of your body are affected. A PET scan can help determine if the tumor is cancerous. A non-cancerous tumor is called benign.
Sometimes, a small piece of the neurofibroma is taken and tested in a lab. This is called a biopsy. A biopsy might be needed if surgery is being considered as a treatment option.
Neurofibromas are tumors that can grow from nerves. If a neurofibroma is small, doesn't cause any problems, and isn't in a spot that's easy to remove surgically, doctors often just watch it. This is called monitoring. Regular checkups and scans (like X-rays or MRIs) make sure the tumor isn't getting bigger.
However, if a neurofibroma is causing pain, numbness, or other problems, or if it's causing an unwanted appearance, surgery might be necessary. Or, if the tumor is growing on many nerves (called a plexiform neurofibroma), there's a medicine that can help.
Treatment options can include:
Monitoring: This is the most common approach for a small, harmless neurofibroma. Your doctor will want to see how the tumor grows over time. They'll schedule regular checkups and imaging tests to look for any changes.
Medication for plexiform neurofibromas: In some cases, particularly for children with a specific type of neurofibroma called a plexiform neurofibroma, a medicine called selumetinib (Koselugo) is approved. This medicine can help shrink the tumor. A plexiform neurofibroma is a type of neurofibroma that grows along many nerves.
Clinical trials: If other treatments aren't working or you're looking for new options, your doctor might suggest joining a clinical trial. Clinical trials test new treatments for conditions like neurofibromatosis. These trials give patients access to experimental treatments under the supervision of medical researchers.
It's important to talk to your doctor about the best treatment plan for your specific situation. The best approach depends on the size, location, and the symptoms of the neurofibroma.
Disclaimer: August is a health information platform and its responses don't constitute medical advise. Always consult with a licenced medical professional near you before making any changes.