Health Library Logo

Health Library

Pcos

Overview

Polycystic ovary syndrome (PCOS) is a common hormonal problem that affects women of reproductive age. It's linked to irregular periods. This means your periods might be infrequent, or they might last unusually long. A key feature of PCOS is having higher-than-normal levels of androgens, which are hormones typically found in higher amounts in men.

Essentially, PCOS involves small fluid-filled sacs, called cysts, growing on the ovaries. These cysts contain immature eggs, called follicles. Normally, the ovaries release mature eggs during a woman's cycle. However, with PCOS, the follicles often don't release these eggs regularly. This irregularity can affect your menstrual cycle and fertility.

What causes PCOS is not fully understood. However, researchers believe it's a combination of genetic and environmental factors. Early diagnosis and treatment are important. Managing PCOS often involves lifestyle changes, like weight loss. This can help reduce the risk of developing long-term health problems, such as type 2 diabetes and heart disease down the line. Regular check-ups with your doctor are crucial for managing PCOS effectively.

Symptoms

Polycystic ovary syndrome (PCOS) often shows up around the time a person's periods first start, but sometimes symptoms develop later. The symptoms aren't always the same from person to person. A doctor diagnoses PCOS if a person has at least two of these problems:

Irregular Periods: This means periods that don't come on a regular schedule. Someone with PCOS might have very few periods, or periods that are very far apart. For example, someone might have fewer than nine periods a year, or their periods might be more than 35 days apart. Periods can also last longer than usual.

High Levels of "Male" Hormones (Androgens): Higher than normal levels of androgens can cause extra hair growth on the face and body (called hirsutism). It can also lead to severe acne or hair loss patterns similar to what men experience.

Cysts on the Ovaries: The ovaries might be larger than normal. A lot of small, fluid-filled sacs (follicles) containing immature eggs may develop around the edges of the ovaries. This can affect how the ovaries work.

How PCOS Affects People: Symptoms of PCOS are often more noticeable in people who are overweight or obese.

When to See a Doctor: If you have concerns about your periods, trouble getting pregnant, or notice signs of extra hair growth, acne, or male-pattern hair loss, it's important to talk to your doctor. These could be signs of PCOS.

When to see a doctor

If you have concerns about your periods, trouble getting pregnant, or notice signs of excess male hormones, see your doctor. These signs can include unwanted hair growth on your face and body, acne, or hair loss following a male pattern. It's important to talk to your doctor about any of these issues, as they could indicate an underlying health condition.

Causes

Polycystic ovary syndrome (PCOS) is a condition affecting women, but the exact cause isn't fully understood. Several factors seem to play a role:

1. Insulin Resistance:

Your pancreas makes insulin, a hormone that helps your body's cells use sugar (glucose) for energy. If your cells don't respond properly to insulin, your blood sugar levels can rise. Your body then produces more insulin to try to bring the sugar levels back down. This extra insulin can lead to your body producing more androgens, which are hormones typically associated with males. This can disrupt ovulation, the process where your ovaries release eggs.

One possible sign of insulin resistance is dark, velvety patches of skin on your neck, armpits, groin, or under your breasts. Increased appetite and weight gain are also potential indicators.

2. Low-Grade Inflammation:

Your body's white blood cells produce substances in response to injury or infection. This response is called inflammation. People with PCOS often have a low-level, ongoing inflammation. This inflammation may cause the polycystic ovaries to produce too much of the male hormone, androgen. This increased androgen can lead to problems with the heart and blood vessels.

3. Genetics (Heredity):

Research suggests that certain genes might increase the risk of developing PCOS. A family history of PCOS can make you more likely to have the condition.

4. Excess Androgens:

In PCOS, the ovaries may produce excessive amounts of androgens. High levels of androgens can interfere with regular ovulation. This means eggs don't develop and release from the follicles (where they grow) as they should. High androgens can also cause unwanted hair growth (hirsutism) and acne.

In summary, PCOS is a complex condition with several potential contributing factors. Insulin resistance, low-grade inflammation, genetics, and excess androgen production all seem to play a role in its development. If you have concerns about these issues, it's important to consult a healthcare professional for diagnosis and treatment.

Complications

Polycystic ovary syndrome (PCOS) can lead to various health problems. One of these is trouble getting pregnant, or infertility. Women with PCOS may also have a higher risk of losing a pregnancy early (miscarriage) or having a baby born too early (premature birth).

PCOS can also increase the chance of developing serious liver problems. This is called nonalcoholic steatohepatitis (NASH). NASH happens when extra fat builds up in the liver, causing inflammation. This can eventually damage the liver if not managed properly.

PCOS is also linked to a higher risk of developing type 2 diabetes or a condition called prediabetes, where blood sugar levels are higher than normal but not yet at the diabetic level. This can lead to other health issues over time.

In addition, some women with PCOS experience sleep apnea, a condition where breathing stops and starts during sleep. This can cause daytime tiredness and other health problems.

Another concern related to PCOS is an increased risk of cancer of the uterine lining, known as endometrial cancer.

Being overweight or obese is frequently seen with PCOS, and extra weight can make the problems associated with PCOS worse. For example, excess weight can worsen insulin resistance, which is often a factor in PCOS and can further increase the risk of diabetes. It can also worsen the symptoms related to liver inflammation. Therefore, maintaining a healthy weight is an important part of managing PCOS.

Diagnosis

Understanding Polycystic Ovary Syndrome (PCOS)

Polycystic ovary syndrome (PCOS) is a condition that affects women's reproductive health. There's no single test to diagnose PCOS, so doctors use a combination of methods to understand your symptoms and health history.

Checking Your Pelvic Area

A doctor might perform a pelvic exam. During this exam, a doctor uses gloved fingers inside the vagina to feel the uterus, ovaries, and other organs. This helps check for any unusual growths, lumps, or other abnormalities.

Using Ultrasound

A transvaginal ultrasound is another common test. This involves lying on your back and having a wand-like device (called a transducer) inserted into your vagina. The transducer sends sound waves, which create images of your ovaries and other pelvic organs on a computer screen. These images can show if your ovaries have many small fluid-filled sacs (follicles), a common feature of PCOS.

Discussing Your Health

Your doctor will likely start by asking about your symptoms, medications, and any other medical conditions you have. They'll also want to know about your menstrual cycle and any weight changes. A physical exam will check for signs like excess hair growth, acne, and insulin resistance, all potentially related to PCOS.

Further Tests (if needed)

Based on the initial assessment, your doctor might recommend further tests. These could include:

  • Blood tests: These measure hormone levels to rule out other conditions that might mimic PCOS symptoms (like problems with menstrual cycles or excess androgens). Blood tests may also include cholesterol, triglyceride, and glucose tolerance tests. A glucose tolerance test checks how your body handles sugar.

  • Ultrasound: An ultrasound can help assess the appearance of your ovaries and the thickness of the uterine lining, which can be important clues.

What if you have PCOS?

If diagnosed with PCOS, your doctor might recommend additional follow-up tests to look for complications. These could include regular checks of blood pressure, blood sugar levels, cholesterol, and triglycerides. They might also screen for depression, anxiety, or obstructive sleep apnea – all conditions that can be linked to PCOS.

Important Note: This information is for general knowledge and understanding. It should not be considered medical advice. Always consult with a healthcare professional for any health concerns or before making any decisions related to your health or treatment.

Treatment

Managing Polycystic Ovary Syndrome (PCOS)

PCOS is a condition that can affect a woman's hormones and menstrual cycle. Treatment focuses on managing the specific problems PCOS causes, which might include difficulty getting pregnant (infertility), unwanted hair growth (hirsutism), acne, or weight issues. Different treatments are available, including lifestyle changes and medication.

Lifestyle Changes:

A key part of PCOS management is often weight loss. Losing weight through a healthy diet and regular exercise can significantly improve symptoms. Even a small amount of weight loss—like losing 5% of your body weight—can make a difference. Losing weight can also increase the effectiveness of any medications your doctor recommends and can help with fertility. Your doctor and a registered dietitian can create a personalized plan to help you lose weight safely and effectively.

Medications:

  • To regulate periods: Birth control pills containing both estrogen and progestin can help regulate periods, reduce the production of male hormones (androgens), and lessen symptoms like irregular bleeding, excess hair growth, and acne. Progestin therapy, taken for a short time each month, can also regulate periods and prevent potential problems with the lining of the uterus (the endometrium). If you don't want to get pregnant, the progestin-only pill or a progestin-containing intrauterine device (IUD) might be better options.

  • To help with fertility:

    • Clomiphene: This medication encourages ovulation, a key step in getting pregnant. It's taken early in the menstrual cycle.
    • Letrozole: This medication, often used for breast cancer, can also stimulate the ovaries to release eggs.
    • Metformin: This medication is typically used to treat type 2 diabetes. It can improve how the body uses insulin, which may help with ovulation and weight loss. If you have prediabetes, metformin can slow the progression to type 2 diabetes. If clomiphene doesn't work, your doctor may add metformin to help.
    • Gonadotropins: These are hormone injections that can stimulate the ovaries to release eggs. If needed, your doctor might discuss procedures like in vitro fertilization (IVF).
  • To reduce hair growth or acne:

    • Birth control pills: As mentioned above, these can help reduce androgens, which can lead to less hair growth and acne.
    • Spironolactone: This medication blocks the effects of androgens on the skin, reducing hair growth and acne. However, it can cause birth defects, so you must use reliable birth control while taking this medicine. Don't take it if you're pregnant or trying to become pregnant.
    • Eflornithine (Vaniqa): This cream can slow facial hair growth.
    • Hair removal: Options include electrolysis (using a small needle to destroy hair follicles) and laser hair removal (using light to target hair follicles). These may require multiple treatments. Shaving, plucking, or using hair removal creams are temporary solutions, and hair growth may be thicker after the treatment.
    • Acne treatments: Various medications, including pills, creams, and gels, can help improve acne. Talk to your doctor about the best options for you.

Important Note: This information is for general knowledge and does not constitute medical advice. Always discuss any symptoms or treatment options with your doctor. They can provide personalized recommendations based on your specific situation.

Preparing for your appointment

If you have Polycystic Ovary Syndrome (PCOS), you might need to see a doctor who specializes in women's reproductive health (a gynecologist), hormone problems (an endocrinologist), or fertility (a reproductive endocrinologist). Here's how to prepare for your appointment.

Before your appointment:

  • Write down your symptoms: What problems are you experiencing, and how long have they lasted?
  • Track your periods: How often do your periods come? How long do they last? How heavy are they?
  • List all medications, supplements, and vitamins: Include the dose of each. This helps the doctor understand everything you're taking.
  • Gather personal and medical information: Tell the doctor about other health conditions, recent life changes (like stress or major events), and any family history of PCOS (like a mother or sister with the condition).
  • Prepare questions: Write down questions for your doctor. It's helpful to have them written down to help you remember. Some key questions include:
    • What tests do you recommend?
    • How might PCOS affect my ability to get pregnant?
    • Are there medicines that could help my symptoms or improve my chances of getting pregnant?
    • What lifestyle changes might help?
    • How could PCOS affect my health in the future?
    • If I have other health conditions, how can I best manage them along with PCOS?

What to expect from your doctor:

Your doctor will likely ask you questions about your symptoms. They'll want to know:

  • What are your symptoms?
  • How often do your symptoms occur?
  • How severe are your symptoms?
  • When did each symptom start?
  • When was your last period?
  • Have you gained weight since you first started having periods? If so, how much and when?
  • Does anything seem to improve or worsen your symptoms?
  • Are you trying to get pregnant, or do you want to become pregnant in the future?
  • Does anyone in your immediate family (mother, sister) have PCOS?

Don't hesitate to ask any other questions that come up during your appointment. Being prepared and asking questions is important for getting the best care.

Address: 506/507, 1st Main Rd, Murugeshpalya, K R Garden, Bengaluru, Karnataka 560075

Disclaimer: August is a health information platform and its responses don't constitute medical advise. Always consult with a licenced medical professional near you before making any changes.

Made in India, for the world