ENA test
About this test
The extractable nuclear antigen test, known as an ENA test, is a blood test that checks for proteins in your blood, also known as antibodies. The ENA test is used to help diagnose certain autoimmune diseases. ENA stands for extractable nuclear antigen because these proteins can be taken out (extracted) from the cells in the body.
Why it's done
Your health care professional may refer you to a doctor trained in autoimmune and arthritis conditions, called a rheumatologist. If the rheumatologist thinks you may have an autoimmune disease, they may order some additional tests.
How to prepare
An ENA test uses a blood sample. If your health care team is only using the blood sample for an ENA test, you can eat and drink as usual before the test. If the blood sample may be used for more tests, you might need to not eat, called fast, for a time before the test. Your health care team will give you directions before the test. Some medicines can affect the test and can cause the test results to show you have autoantibodies when you don't. So bring your health care team a list of the medicines and supplements you take.
What to expect
For an ENA test, a member of your health care team takes a blood sample by inserting a needle into a blood vessel, called a vein, in your arm. The blood sample goes to a lab for testing. You can return to your usual activities right away.
Understanding your results
Your ENA test is positive if test results show the blood sample has autoantibodies. Your rheumatologist can use a positive ENA test result, along with a physical exam and other tests, to see if you have certain autoimmune diseases. ENA test results can be hard to understand. Generally, an expert should review the results. It's important to talk about the results with your rheumatologist and ask any questions you may have.
Disclaimer: August is a health information platform and its responses don't constitute medical advise. Always consult with a licenced medical professional near you before making any changes.